Molecule viewer

BPC-157

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Proposed to promote angiogenesis and modulate nitric oxide and VEGF signalling, accelerating healing of tendon, ligament, muscle and gut tissue in animal injury models. No validated human receptor or pharmacokinetic profile has been published, and nearly all supportive data come from a small cluster of laboratories using rodent models.

Category
Tissue repair & healing
Evidence
Animal / in-vitro only
Residues
15
Mass
≈1419 Da

Sequence

GEPPPGKPADDAGLV

Mechanisms

  • Pentadecapeptide fragment of a protective protein found in human gastric juice
  • Unusually stable in gastric acid for a peptide of its size
  • No confirmed receptor; proposed action through VEGF and nitric-oxide signalling

Regulatory status

Not approved by FDA or EMA. Investigated as PL 14736 for inflammatory bowel disease but never marketed. Prohibited in sport (WADA).

Studies

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